This report focusses attention on known sources of pollution and provides a priority for action to correct existing water pollution problems and prevent future problems in the Verdigris River, an interstate stream, and its tributaries. Pollution problems indicated by septic conditions, oxygen depletion, and high sulfate, chloride, and dissolved solids concentrations, are degradations of aesthetics, damages to propagation of fish life, degradation of municipal and industrial water supplies, and impairment of water for recreational uses. Immediate pollution control needs are in waste treatment, flow regulation, institutional practices, and research.