Nutrient and suspended-sediment (SS) samples were collected under base flow and stormflow conditions during calendar year 2004 for Group A sites listed in Table 2. Fixed date samples also were collected at these sites. Additionally, fixed date samples were collected during the fourth quarter of 2004 at Group B sites listed in Table 2. All samples were analyzed for nitrogen and phosphorus species, total organic carbon (TOC), and SS. Precipitation for 2004 was above average for all Group A sites. Highest departures from the long-term precipitation averages were recorded at Newport with 14.3 inches above the long-term mean (LTM). Highest departure from LTM in discharge was 157.9 percent above LTM at Conestoga. Lowest departure from the mean was at Towanda for rainfall, 9.16 inches above LTM and at Danville for flow at 127.7 percent of the LTM. Precipitation and flows were above LTM largely due to high flows caused by Tropical Storm Ivan in September. This report utilizes four methods to analyze nutrient and SS loads and yields: (1) comparison with the LTM; (2) comparison with initial 5-year baseline yields; (3) comparison with baseline data from the beginning of program through 2004 (full program baseline); and (4) flow adjusted trend analysis through 2004. Comparison with the LTM showed increases in flow, total phosphorus (TP), and SS for all sites except for SS at Lewisburg. Increases in total nitrogen (TN) were shown at Newport and Marietta when compared to the LTMs. Baseline comparisons showed increases in TN at Newport, increases in TP at all sites except Conestoga, and increases in SS at all sites except Conestoga and Lewisburg, when compared to the initial 5-year baselines. When compared to the full program baseline, Newport showed increases in all three parameters, Marietta and Danville showed increases in TP, and all sites except Conestoga and Lewisburg showed increases in SS. Trends in flow-adjusted concentrations (FACs) were found to be decreasing for TN, TP, and SS at all sites except for TP at Marietta, which showed no significant trends. No significant trends were found for flow.