Record Display for the EPA National Library Catalog


Main Title Toxicological review of tetrahydrofuran (CAS No. 109-99-9) : in support of summary information on the Integrated Risk Information System (IRIS) /
Other Authors
Author Title of a Work
Dannan, Ghazi A.
Lai, David.
Margosches, Elizabeth.
CORP Author Environmental Protection Agency, Washington, DC. National Center for Environmental Assessment.
Publisher U.S. Environmental Protection Agency,
Year Published 2012
Report Number EPA/635/R-11/006F
Stock Number PB2012-108148
OCLC Number 779978088
Subjects Tetrahydrofuran--Toxicology
Additional Subjects Toxicity ; Tetrahydrofuran ; Health hazards ; Dose response relationships ; Cancer ; Environmental exposure ; Chemical properties ; Risk assessment ; Integrated Risk Information System(IRIS) ; CAS No 109-99-9
Internet Access
Description Access URL
Library Call Number Additional Info Location Last
EJAI  via Internet only Region 3 Library/Philadelphia, PA 05/30/2012
NTIS  PB2012-108148 Some EPA libraries have a fiche copy filed under the call number shown. 07/26/2022
Collation [207] pages : illustrations, color graphs ; digital, PDF file
The purpose of this toxicological review is to provide scientific support and rationale for the hazard and dose-response assessment in IRIS pertaining to chronic exposure to tetrahydrofuran. It is not intended to be a comprehensive treatise on the chemical or toxicological nature of tetrahydrofuran. The intent of Section 6, Major Conclusions in the Characterization of Hazard and Dose Response, is to present the major conclusions reached in the derivation of the reference dose, reference concentration and cancer assessment, where applicable, and to characterize the overall confidence in the quantitative and qualitative aspects of hazard and dose response by addressing the quality of data and related uncertainties. The discussion is intended to convey the limitations of the assessment and to aid and guide the risk assessor in the ensuing steps of the risk assessment process.
Title from PDF title screen (viewed 3/13/2012). Includes bibliographical references. "February 2012." "EPA/635/R-11/006F."
Contents Notes
"This document presents background information and justification for the Integrated Risk Information System (IRIS) Summmary of the hazard and dose-response assessment of tetrahydrofuran (THF). IRIS Summaries may include oral reference dose (RfD) and inhalation reference concetration (RfC) values for chronic and other exposure durations, and a carcinogenicity assessment." p. 15.