Record Display for the EPA National Library Catalog
RECORD NUMBER: 830 OF 1511| Main Title | Pathologic Changes in the Liver of Rats after Feeding Low Levels of Various Insecticides. | |||||||||||
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| Author | Ortega, Paul ; Hayes, Wayland J. ; Durham., William F. ; | |||||||||||
| CORP Author | Communicable Disease Center, Savannah, Ga. | |||||||||||
| Year Published | 1957 | |||||||||||
| Stock Number | PB-279 717 | |||||||||||
| Additional Subjects | Pesticides ; Toxicology ; Morbidity ; Mortality ; Liver ; Rats ; Pathology ; Ingestion(Biology) ; Insecticides ; Body weight ; Diet ; Laboratory animals ; Experimental data ; Tissues(Biology) ; Kidney ; Spleen ; Dieldrin ; Chlordan ; Dosage ; Toxicity ; Reprints ; Lindane ; Toxaphene ; Toxic substances | |||||||||||
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| Collation | 9p | |||||||||||
| Abstract | In order to reinvestigate the minimal dietary levels of certain chlorinated hydrocarbon insecticides required to produce pathologic change, materials were fed to rats at the following concentrations: Chlordane, 2.5 and 25 ppm; Dieldrin, 2.5 and 25 ppm; lindane, 50 and 100 ppm; and Toxaphene, 50 and 200 ppm. The control diet contained less than 0.6 ppm of D.D.T. as the only known contaminating insecticide. The experimental animals were observed clinically and then serially killed after from two to nine months' exposure to the poison. Tissues from liver, kidney, and spleen were examined histologically. (Portions of this document are not fully legible) |