Record Display for the EPA National Library Catalog

RECORD NUMBER: 594 OF 1511

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Main Title

Identification of Five Unreported Lindane Metabolites Recovered from Rat Urine.

Author

Chadwick, R. W. ; Freal., J. J. ;

CORP Author

Environmental Protection Agency, Perrine, Fla. Perrine Primate Lab.

Year Published

1972

Stock Number

PB-275 925

Additional Subjects

Chlorobenzenes ; Insecticides ; Pesticides ; Chlorine aromatic compounds ; Identifying ; Rats ; Urine ; Experimental data ; Laboratory animals ; Tables(Data) ; Diet ; Metabolism ; Isolation ; Ingestion(Biology) ; Excretion ; Metabolites ; Lindane ; Reprints

Holdings

Library	Call Number	Additional Info	Location	Last Modified	Checkout Status
NTIS	PB-275 925	Some EPA libraries have a fiche copy filed under the call number shown.		07/26/2022

Collation

10p

Abstract

Previously unreported metabolites from the urine of rats fed lindane have been identified as 3,4-dichlorophenol, 2,4,6-trichlorophenol, 2,3,4,5-tetrachlorophenol, 2,3,4,6-tetrachlorophenol and 2,3,4,5,6-pentachloro-2-cyclohexen-1-ol. While the 3,4-dichlorophenol is a minor metabolite, the others are excreted in greater quantities than either 2,3,5- or 2,4,5-trichlorophenol, previously identified lindane metabolites. The excretion of tetrachlorophenols and PCCOL require a revision in the currently accepted theory regarding the metabolism of lindane by mammals.

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