Record Display for the EPA National Library Catalog

RECORD NUMBER: 594 OF 1325

Main Title Initial Submission: Subacute Inhalation Toxicity of Chloroformic Acid Methyl Ester in Rats with Cover Letter dated 07/17/1993.
CORP Author BASF Corp., Mount Olive, NJ.; Environmental Protection Agency, Washington, DC. Office of Toxic Substances.
Year Published 1993
Report Number 8EHQ-0693-10193
Stock Number OTS0570775
Additional Subjects Toxicology ; Health effects ; Toxic substances ; Chloroformic acid ; Methyl ester ; Subchronic toxicity ; Mammals ; Rats ; Inhalation ; CAS No 79-22-1
Holdings
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Status
NTIS  OTS0570775 Some EPA libraries have a fiche copy filed under the call number shown. 07/26/2022
Collation 5p
Abstract
BASF has knowledge of results of a subacute inhalation toxicity study of chloroformic acid methyl ester (CAS No. 79-22-1) sponsored by BG Chemie, P.O. Box 101480, 6900 Heidelberg, Germany (Employment Accident Insurance Fund of the Chemical Industry). Although BASF does not feel that the information presents a substantial risk to health or environment, it is being submitted under Section 8(e) of TSCA. A subacute inhalation toxicity study in male and female Sprague- Dawley rats was performed according to OECD-Guideline No. 412 and EEC method B.8. Groups of five animals/sex were exposed to air (control) and five different concentrations of CFAME 6 hours per day, 5 days per week for 4 weeks. The concentrations were: 0.52 mg/m (low), 1.48 mg/m (low intermediate), 3.94 mg/m (intermediate), 12.14 mg/m (high intermediate), and 34.36 mg/m (high).