| Main Title |
Letter from Du Pont to Inform the USEPA of Preliminary Results of a Range-Finding Inhalation (ALC) Test in Rats with Benzyltriphenylphosphonium Chloride and MSDS Attached. |
| CORP Author |
Du Pont de Nemours (E.I.) and Co., Newark, DE. Haskell Lab. for Toxicology and Industrial Medicine.;Environmental Protection Agency, Washington, DC. Office of Toxic Substances. |
| Publisher |
8 Feb 1988 |
| Year Published |
1988 |
| Report Number |
8HEQ-0288-0296; |
| Stock Number |
OTS-0200638-1 |
| Additional Subjects |
Inhalation ;
Toxicity ;
Rats ;
Exposure(Physiology) ;
Chemical analysis ;
Irritation ;
Lethal dosage ;
Clinical signs ;
Laboratory tests ;
US EPA ;
Respiratory distress ;
Urine ;
Samples ;
Benzyltriphenylphosphoniuym chloride(BTPPC)
|
| Holdings |
| Library |
Call Number |
Additional Info |
Location |
Last
Modified |
Checkout
Status |
| NTIS |
OTS-0200638-1 |
Some EPA libraries have a fiche copy filed under the call number shown. |
|
07/26/2022 |
|
| Collation |
17p |
| Abstract |
This document presents the preliminary results of a range-finding inhalation test in rats with benzyl-triphenylphosphonium chloride (BTPPC). BTPPC was the subject of an B(e) report filed by Cincinnati Milacron Chemicals on July 18, 1979 (8EHQ-0779-0296) in which acute toxicity and irritation was observed as the result of oral and ocular exposures. Du Pont purchases BTPPC and decided to conduct a subchronic inhalation study to determine the inhalation toxicity of this material. The initial test is a range-finding study known as an ALC (Approximate Lethal Concentration) test. In this test, groups of 6 male rats are exposed by inhalation to atmospheres containing various respirable concentrations of BIPPC for single 4-hour periods. The results of this initial test will be used to determine exposure levels in a subchronic repeated exposure inhalation study. |
