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RECORD NUMBER: 25 OF 44

Main Title Letter from Union Carbide Chemical and Plastic Company to USEPA containign Preliminary Lab Findings from Immune System Toxicology Study with Attachments.
CORP Author Union Carbide Corp., Danbury, CT.;Environmental Protection Agency, Washington, DC. Office of Toxic Substances.
Publisher 12 Mar 1991
Year Published 1991
Report Number 8HEQ-0391-0347;
Stock Number OTS-0204852-4
Additional Subjects Immunology ; Toxicology ; Rats ; Lethal dosage ; Toxicity ; Exposure ; Vapors ; Inflammation ; Respiratory system ; Dose-response relationships ; Injuries ; Lympoid tissue ; Laboratory animals ; Laboratory tests ; US EPA ; Trimethoxysilane ; Union Carbide Chemicals and Plastics Company
Holdings
Library Call Number Additional Info Location Last
Modified
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Status
NTIS  OTS-0204852-4 Some EPA libraries have a fiche copy filed under the call number shown. 07/26/2022
Collation 20p
Abstract
The reports described a moderately high lethal inhalation toxicity of TMS to rats by exposure to vapor generated at ambient temperature. This was associated with severe injury and inflammation to the respiratory tract. The 1980 report was concerned with the effects of repeated exposures, and the 1988 supplemental report with an acute vapor exposure study. In order to more precisely define the concentration-response relationships for the known toxicity of TMS vapor, a short-term repeated vapor inhalation study is currently being conducted with rats. The information available to date confirms the lethal toxicity and respiratory tract injury.