Record Display for the EPA National Library Catalog


Main Title Developing Improved Strategies to Determine Male Reproductive Risk from Environmental Toxins.
Author Berndtson, W. E. ; Clegg, E. D. ;
CORP Author Environmental Protection Agency, Washington, DC. Reproductive and Developmental Toxicology Branch. ;New Hampshire Univ., Durham. Dept. of Animal and Nutritional Sciences.
Publisher c1992
Year Published 1992
Report Number EPA/600/J-93/047 ;OHEA-R-469;
Stock Number PB93-167286
Additional Subjects Reproduction(Biology) ; Environmental pollutants ; Toxicology ; Male infertility ; Testis ; Spermatozoa ; Histology ; Animals ; Reprints ;
Library Call Number Additional Info Location Last
NTIS  PB93-167286 Some EPA libraries have a fiche copy filed under the call number shown. 07/26/2022
Collation 17p
It is important that evaluation procedures for chemicals incorporate measures suitable to detect a wide range of potential effects from those chemicals. The reproductive systems are among the most sensitive to toxic insult, so it is important that effective methods be developed and applied for detection of reproductive effects and protection of reproductive capability. As adequate data on the effects of human exposures are seldom available, it is necessary then to use data from other species. Species used most frequently are rodents, rabbits, dogs and subhuman primates. Knowledge gained from research with farm species is being applied in the design of improved protocols to detect health effects. Included are important contributions in developing new evaluation tests, improved experimental design and in furthering understanding of reproductive biology. The paper addresses several testing and risk assessment issues in male reproductive toxicology that form the basis for some of the authors' research.