Record Display for the EPA National Library Catalog

RECORD NUMBER: 368 OF 663

Main Title Initial Submission: Mutagenicity Evaluation of 1,6-Hexanediol Diacrylate in the Mouse Lymphoma Forward Mutation Assay with Cover Letter dated 09/04/1992.
CORP Author Litton Bionetics, Inc., Bethesda, MD.; Rhone-Poulenc Ag Co., Research Triangle Park, NC.; Environmental Protection Agency, Washington, DC. Office of Toxic Substances.
Year Published 1992
Report Number 8EHQ-0992-11048
Stock Number OTS0571083
Additional Subjects Toxicology ; Health effects ; Toxic substances ; 1 ; 6 hexanediol diacrylate ; Genotoxicity ; Gene mutation ; Mammals ; Mice ; In vitro ; CAS No 13048-33-4
Holdings
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Status
NTIS  OTS0571083 Some EPA libraries have a fiche copy filed under the call number shown. 07/26/2022
Collation 15p
Abstract
This study is being reported under Section 8(e) CAP because acrylates generally produce positive results in the mouse lymphoma assay. In this study, the test material induced an increase in the mutant frequency at the TK Locus in L5178Y mouse lymphoma cells at concentrations of 0.0094 and 0.0125 pl/ml without activation. No increase in mutant frequency was observed with activation.