Record Display for the EPA National Library Catalog


Main Title Interactions of Various Air Pollutants on Causation of Pulmonary Disease.
Author Fenter, James D. ; Maigette, Robert Z. ;
CORP Author IIT Research Inst., Chicago, Ill.
Year Published 1973
Report Number EPA-68-02-0666; 650/1-73-002;
Stock Number PB-230 933
Additional Subjects Air pollution ; Respiratory diseases ; Public health ; Nitrogen dioxide ; Manganese ; Bacterial diseases ; Mice ; Immunization ; Histology ; Serology ; Lung ; Pneumonia ; Exposure ; Viral diseases ; Infectious diseases ; Pneumonia ; Influenza virus ; Immunoglobulins ; Hemagglutination inhibition tests
Library Call Number Additional Info Location Last
NTIS  PB-230 933 Some EPA libraries have a fiche copy filed under the call number shown. 07/26/2022
Collation 56p
The report consists of four studies. The materials, methods, and experimental protocol for each study were presented. The parameters of interest were hemagglutination-inhibition (HI) and serum neutralization (SN) antibody formation, serum immunoglobulin levels, lung histopathology, mortality rates, lung lesion scores, and extent of lung edema in mice. The four studies were: immune response in mice during long term exposure to nitrogen dioxide, immune response in mice during a four-week exposure to NO2, effect of chronic exposure to NO2 on resistance to Klebsiella pneumoniae, and effects of manganese on resistance to respiratory infection. In the first study prior to vaccination the mice were exposed continuously to 2ppm NO2, 0.5ppm NO2 with one-hr daily peaks of 2ppm NO2 5 days in a week, or filtered air for three months. They were thereafter held in either an NO2 environment or filtered air.