Introduction to the immune system. Properties and overview of immune responses ; Innate immunity ; Cells and tissues of the adaptive immune system -- Recognition of antigens. Antibodies and antigens ; The major histocompatibility complex ; Antigen processing and presentation to T lymphocytes ; Antigen receptors and accessory molecules of T lymphocytes -- Maturation, activation and regulation of lymphocytes. Lymphocyte development and the rearrangement and expression of antigen receptor genes ; Activation of T lymphocytes ; B cell activation and antibody production ; Immunological tolerance -- Effector mechanisms of immune responses. Cytokines ; Effector mechanisms of cell-mediated immunity ; Effector mechanisms of humoral immunity -- The immune system in defense and disease. Immunity to microbes ; Transplantation immunology ; Immunity to tumors ; Diseases caused by immune responses : hypersensitivity and autoimmunity ; Immediate hypersensitivity ; Congenital and acquired immunodeficiencies -- Appendix I: Glossary -- Appendix II: Principal features of selected CD molecules -- Appendix III: Laboratory techniques commonly used in immunology. This book offers an exceptionally lucid guide to the latest immunology concepts! Readers worldwide have appreciated the book's in-depth yet straightforward, richly illustrated approach to this complex subject. Now, sweeping updates incorporate the latest discoveries about innate immunity, the organization of lymphoid organs, and many other cutting-edge topics. Plus, online access via Student Consult makes this an even more powerful learning resource! Clearly explains the experimental observations that form the basis for the science of immunology at the molecular, cellular, and whole-organism levels-and the conclusions that can be drawn from those observations.