Record Display for the EPA National Library Catalog


OLS Field Name OLS Field Data
Main Title Hypothermia and Chloropent Anesthesia Differentially Affect the Flash Evoked Potentials of Hooded Rats.
Author Dyer, R. S. ; Boyes, W. K. ;
CORP Author Health Effects Research Lab., Research Triangle Park, NC.
Year Published 1983
Report Number EPA/600/J-83-050;
Stock Number PB84-101278
Additional Subjects Anesthetics ; Hypothermia ; Electrophysiology ; Brain ; Body temperature ; Rats ; Laboratory animals ; Reprints ; Evoked potentials ; Chloropent
Library Call Number Additional Info Location Last
NTIS  PB84-101278 Most EPA libraries have a fiche copy filed under the call number shown. Check with individual libraries about paper copy. 06/23/1988
Collation 10p
Anesthetics and body temperature alterations are both known to alter parameters of sensory-evoked responses. However few studies have quantitatively assessed the contributions of hypothermia to anesthetic-induced changes. Two experiments were performed. In the first, chronically implanted rats were injected with either 0, 0.05, 0.10 or 0.20 ml Chloropent/100 gb.w, while body temperature was maintained. Flash evoked potentials recorded 30 min later showed increased latencies but only minor (not statistically significant) changes in amplitude. In the second experiment the same rats were anesthetized with 0.35 ml Chloropent/100 g b.w. and rectal temperature was systematically varied between 31C and 37C.