| Main Title |
Initial Submission: Subacute Oral Gavage Toxicity of Poly(Difluoromethylene) A-Fluoro-B-2-Hydroxy-Ethyl in Rats with Cover Letter dated 09/02/1992. |
| CORP Author |
Du Pont de Nemours (E.I.) and Co., Newark, DE. Haskell Lab. for Toxicology and Industrial Medicine.; Environmental Protection Agency, Washington, DC. Office of Toxic Substances. |
| Year Published |
1992 |
| Report Number |
8EHQ-0992-10993 |
| Stock Number |
OTS0571031 |
| Additional Subjects |
Toxicology ;
Health effects ;
Toxic substances ;
Poly(difluoromethylene) a-fluoro-b-2-hydroxy-ethyl ;
Subchronic toxicity ;
Mammals ;
Rats ;
Oral ;
Gavage ;
CAS No 65530-60-1 ;
CAS No 71215-70-8
|
| Holdings |
| Library |
Call Number |
Additional Info |
Location |
Last
Modified |
Checkout
Status |
| NTIS |
OTS0571031 |
Some EPA libraries have a fiche copy filed under the call number shown. |
|
07/26/2022 |
|
| Collation |
29p |
| Abstract |
Zonyl BA (TLF-18k7) was administered orally to 10 young adult male ChR-CD rats at 1700 mg/kg/day. None survived the planned dosing period. One animal died after having received 3 of 10 planned doses; 3 more were found dead after receiving the fourth dose; the reminder died after having received 5 doses. The test compound was then given to a second group of 10 rats at 850 ag/kg/day. Four animals failed to survive the planned dosing period. Of the 6 survivors, 5 were killed on the last day of the dosing period and 2 were killed after a 14-day recovery period. |
