Record Display for the EPA National Library Catalog


Main Title Guidelines for reproductive toxicity risk assessment : draft.
Author Clegg., E.
Other Authors
Author Title of a Work
Clegg, Eric D.
CORP Author Environmental Protection Agency, Washington, DC. Office of Health and Environmental Assessment.
Publisher U.S. Environmental Protection Agency, Office of Research and Development, Office of Health and Environmental Assessment,
Year Published 1994
Report Number EPA/600-AP-94-001; OHEA-R-558
Stock Number PB94-155827
OCLC Number 30047996
Subjects Reproductive toxicology--Government policy ; Human reproduction--Effect of chemicals on ; Health risk assessment
Additional Subjects Toxicity ; Risk assessment ; Reproduction(Biology) ; Testings ; Males ; Females ; Exposure ; Biological accumulation ; Fertility ; Dose-response relationships ; Biological markets ; Histology
Internet Access
Description Access URL
Library Call Number Additional Info Location Last
EHBD  EPA/600/AP-94/001 CEMM/ACESD Library/Narragansett,RI 02/16/2007
EJED  EPA 600/AP-94/001 OCSPP Chemical Library/Washington,DC 04/01/1994
EKBD  EPA/600/AP-94/001 Research Triangle Park Library/RTP, NC 04/15/1994
EKCD  EPA/600/AP-94/001 CEMM/GEMMD Library/Gulf Breeze,FL 10/02/2018
ELBD ARCHIVE EPA 600-AP-94-001 Received from HQ AWBERC Library/Cincinnati,OH 10/04/2023 DISPERSAL
ERAD  EPA 600/AP-94-001 Region 9 Library/San Francisco,CA 01/01/1988
ESAD  EPA 600-AP-94-001 Region 10 Library/Seattle,WA 01/02/1998
NTIS  PB94-155827 Some EPA libraries have a fiche copy filed under the call number shown. 07/26/2022
Collation vi, 134 pages ; 28 cm
In 1988, EPA published separate Proposed Guidelines for Assessing Male Reproductive Risk and Proposed Guidelines for Assessing Female Reproductive Risk. Changes made based on previous public comment and SAB review include combining the separate guidelines for assessing male and female reproductive risk into a single document, integrating the hazard identification and dose-response sections, assuming as a default that an agent for which sufficient data are available on only one sex may also affect reproductive function in the other sex, expansion of the section on interpretation of female endpoints, and consideration of the benchmark dose approach for quantitative risk assessment. This external review draft document will be revised after public review and comment.
"Draft, do not quote or cite." "EPA/600-AP-94-001." "February 1994." "This external review draft was prepared by an intra-Agency EPA working group chaired by Eric Clegg of the Office of Health and Environmental Assessment"--Page vi.