Record Display for the EPA National Library Catalog


Main Title Incomplete Studies with Cover Letter.
CORP Author Mobil Oil Corp., New York.;Environmental Protection Agency, Washington, DC. Office of Toxic Substances.
Publisher 20 Aug 1982
Year Published 1982
Report Number 878210559;
Stock Number OTS-0206118
Additional Subjects Mutagenesis ; Toxicity ; Rats ; Liver ; Metabolic activation ; Toxicology ; Bacteria ; Assays ; Homogenates ; Doses ; Chlorinated paraffins ; Salmonella
Library Call Number Additional Info Location Last
NTIS  OTS-0206118 Some EPA libraries have a fiche copy filed under the call number shown. 07/26/2022
Collation 31p
XRR 185A (TACU no. 8259) was tested in the Ames Salmonella Pre-Incubation Assay with metabolic activation by Aroclor 1254 induced rat liver homogenate (S-9) at doses of 1.0 micro1, 0.50 micro1, 0.30 micro1, 0.10 microl and 0.05 microl test substance per bacterial plate and without metabolic activation by S-9 at doses of 0.10 micro1, 0.07 microl, D.05 microl, 0.03 micro1 and 0.01 micro1 test substance per bacterial plate in strains TA98, TA100, TA1535, TA1537 and TA1538. In preliminary toxicity studies at a dose of 0.30 microl/50 microl without S-9 in tester strains TA100 and TA1537 the background bacterial lawn was extremely reduced and microcolonies were present. In both of these tester strains at a dose of 3.1 microl/50 microl with S-9 the background bacterial lawn was moderately reduced. The reduction of the background bacterial lawn and the presence of microcolonies indicate sufficient solubility for interaction of the bacteria with the test material . The results of the assay indicate that XRR 185A had no mutagenic activity in this test system.