Record Display for the EPA National Library Catalog

RECORD NUMBER: 55 OF 155

Main Title Estimation of Octanol/Water Partition Coefficients for Organic Pollutants Using Reverse-Phase HPLC.
Author McDuffie, Bruce ;
CORP Author Environmental Research Lab., Athens, GA.
Year Published 1981
Report Number EPA/600/J-81-286;
Stock Number PB81-230872
Additional Subjects Water pollution ; Partitions(Mathematics) ; Organic compounds ; Soils ; Sediments ; Solutes ; Reprints ; Octanol ; High performance liquid ; Chromatography ; Numerical solution
Holdings
Library Call Number Additional Info Location Last
Modified		 Checkout
Status
NTIS  PB81-230872 Some EPA libraries have a fiche copy filed under the call number shown. 07/26/2022
Collation 13p
Abstract
Octanol/water partition coefficients (K(ow's)) of organic solutes are estimated with reasonable accuracy (standard deviation + or - 0.25 log K(ow)units) by elution from a C-18 column with 75:25 (v/v) MeOH-H20, based on results with 37 test compounds. Changes in solute activity coefficients from water to 75% MeOH account for the slope of the log K(ow)-log k' plot, where k' is the HPLC capacity factor. The method is used to estimate K(ow)'s for 25 additional organic compounds, and some disparities between the results and those calculated using group addivity-constitutive factors are noted.