Record Display for the EPA National Library Catalog

RECORD NUMBER: 19 OF 22

Main Title Predicting the Carboxyhemoglobin Levels Resulting from Carbon Monoxide Exposures.
Author Peterso, Jack E. ; Stewar, Richard D. ;
CORP Author Medical Coll. of Wisconsin, Milwaukee. Dept. of Environmental Medicine.
Year Published 1973
Report Number MCOW-ENVM-CO-73-1; APRAC-CAPM-3-68; 3-68-4;
Stock Number PB-223 892
Additional Subjects ( Carbon monoxide ; Hemoglobins) ; Exposure ; Sex ; Exercise ; Inhalation ; Lung ; Dosage ; Numerical analysis ; Empirical equations ; Oxygen ; Predictions ; Carbonylhemoglobin
Internet Access
Description Access URL
https://nepis.epa.gov/Exe/ZyPDF.cgi?Dockey=9100KXTI.PDF
Holdings
Library Call Number Additional Info Location Last
Modified		 Checkout
Status
NTIS  PB-223 892 Some EPA libraries have a fiche copy filed under the call number shown. 07/26/2022
Collation 49p
Abstract
The report consists of data from a series of human exposures to carbon monoxide which were analyzed to determine the fit to the theoretical Coburn, Forster, Kane (CFK) equation as a function of experiment duration and CO concentration, exercise level, and sex. The equation was found to predict carboxyhemoglobin (COHb) levels for both men and women at exercise rates ranging from sedentary to 300 kp-m/min when they were exposed to steady CO concentrations of 50, 100, and 200 ppm for 0.33 to 5.25 hours. In addition, the equation accurately summed the results of a discontinuous exposure to CO. Methods for determining values of each of the variables in the CFK equation were collected and a rational, efficient procedure for solving the equation was then used to prepare a graph relating COHb saturation to exposure duration and concentration, and also to describe the effect of several variables on the rate of CO uptake and equilibrium COHb levels. Portions of this document are not fully legible.