||Half-Life of Polychlorinated Biphenyls in Occupationally Exposed Workers.
Phillips, D. L. ;
Smith, A. B. ;
Burse, V. W. ;
Steele, G. K. ;
Needham., L. L. ;
||Corvallis Environmental Research Lab., OR. ;Centers for Disease Control, Atlanta, GA. Center for Environmental Health and Injury Control. ;Indiana State Board of Health, Indianapolis. ;National Inst. for Occupational Safety and Health, Cincinnati, OH. Div. of Surveillance, Hazard Evaluations and Field Studies.
Half life ;
Occupational exposure ;
Polychlorobiphenyl compounds ;
Enzyme induction ;
Environmental exposure pathways ;
||Some EPA libraries have a fiche copy filed under the call number shown.
In 1977 and 1985, serum polychlorinated biphenyl (PCB) concentrations were determined for 58 workers in a Bloomington, Indiana, factory that used PCBs in capacitor manufacture until 1977. Less chlorinated PCBs were quantitated as Aroclor 1242, and more highly chlorinated PCBsw were quantitated as Aroclor 1254. The median half-life was 2.6 y for Aroclor 1242 and 4.8 y for Aroclor 1254. However, the half-life varied inversely with the initial serum concentration. This pattern may be a result of continued low-level exposure, variation in the time of exposure, or enzyme induction by PCBs.