Record Display for the EPA National Library Catalog

RECORD NUMBER: 4 OF 7

OLS Field Name OLS Field Data
Main Title Letter from Gulf Oil Company to USEPA Regarding Information on the Mutation Assay and In Vitro Cell Transformation Testing Conducted at EG&G Mason Laboratories.
CORP Author Gulf Refining and Marketing Co., Houston, TX.;Environmental Protection Agency, Washington, DC. Office of Toxic Substances.
Publisher 9 Feb 1981
Year Published 1981
Report Number 8HEQ-0281-0385;
Stock Number OTS-0204916
Additional Subjects Mutations ; Cells(Biology) ; Toxicology ; In vitro analysis ; Rats ; Lymphomas ; Metabolism ; Exposure(Physiology) ; Bioassay ; Cultures(Biology) ; Plates ; Laboratory tests ; US EPA ; Gulf Oil Company
Holdings
Library Call Number Additional Info Location Last
Modified
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Status
NTIS  OTS-0204916 Most EPA libraries have a fiche copy filed under the call number shown. Check with individual libraries about paper copy. 07/09/2008
Collation 332p
Abstract
This test involves the growth of mice cells in culture dishes in the presence of the material being tested (the experimental protocol used is a modification of that described by Clive, D. and Spector, J.F.S., Laboratory Procedure for Assessing Specific Locus Mutations at the TK Locus in Cultured L5178Y Mouse Lymphoma Cells. Mutation Research 31:17-29, (1975)). After the 'exposure' period, the cells are washed and placed in a growth medium which restricts the growth of 'normal' cells. Only mutant cells should grow in this medium. Control groups are used to detect the growth of any non-exposed cells in the medium.