Record Display for the EPA National Library Catalog
RECORD NUMBER: 97 OF 326
|OLS Field Name||OLS Field Data|
|Main Title||Initial Submission: Epichlorohydrin Toxicity and Safety Bulletin with Cover Letter dated 10/27/1992.|
|CORP Author||Shell Oil Co., Houston, TX.; Rhone-Poulenc Ag Co., Research Triangle Park, NC.; Environmental Protection Agency, Washington, DC. Office of Toxic Substances.|
|Additional Subjects||Toxicology ; Health effects ; Epichlorohydrin ; Acute toxicity ; Mammals ; Mice ; Inhalation ; Rats ; Guinea pigs ; Rabbits ; Oral ; Dermal ; Parenteral ; Intraperitoneal ; CAS No 106-89-8|
The enclosed information is being submitted under Section 8(e) CAP, because EPA may not have been aware of all of the results summarized in these documents at the time they were issued. For example, the acute toxicity data may not have been known to EPA in 1977. These data show epichlorohydrin to be moderately toxic via inhalation resulting in cyanosis followed by muscular relaxation of the extremities. Similar effects were observed following oral, dermal, and subcutaneous exposures. Epichlorohydrin was also reported to be irritating and to produce dermatitis and allergic skin reactions.