Record Display for the EPA National Library Catalog

RECORD NUMBER: 80 OF 326

OLS Field Name OLS Field Data
Main Title Initial Submission: Acute Oral Toxicity and Skin Absorption and Irritation of 3-Chloropropionitrile in Rats and Guinea Pigs with Cover Letter dated 08/26/1992.
CORP Author Eastman Kodak Co., Rochester, NY.; Environmental Protection Agency, Washington, DC. Office of Toxic Substances.
Year Published 1992
Report Number EPA-OTS-88-920009469
Stock Number OTS0571125
Additional Subjects Toxicology ; Health effects ; 3-Chloroproprionitrile ; Acute toxicity ; Mammals ; Rats ; Oral ; Gavage ; Primary dermal irritation ; Guinea pigs ; Dermal ; CAS No 542-76-7
Holdings
Library Call Number Additional Info Location Last
Modified
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Status
NTIS  OTS0571125 Most EPA libraries have a fiche copy filed under the call number shown. Check with individual libraries about paper copy. 05/27/2010
Collation 5p
Abstract
The report pertains to 3-chloropropanenitrile (synonym: 3-chloropropionitrile) (CAS No. 542-76-7) and is being submitted because of lethality with central nervous system (CNS) signs observed in an acute oral toxicity study in rats. The oral LD50 is 10-50 mg/kg in rats. The material is also a slight skin irritant. The dermal LD50 is 0.05-0.1 cc/kg in guinea pigs. The report is being identified as a study involving other than human effects (Unit II.B.2.b of CAP Agreement).