Record Display for the EPA National Library Catalog

RECORD NUMBER: 79 OF 326

OLS Field Name OLS Field Data
Main Title Initial Submission: Acute Oral and Dermal Toxicity of B-Aminocrotonitrile in Rats, Mice, and Guinea Pigs with Cover Letter dated 09/08/1992.
CORP Author Eastman Kodak Co., Rochester, NY.; Environmental Protection Agency, Washington, DC. Office of Toxic Substances.
Year Published 1992
Report Number 8EHQ-0992-10989
Stock Number OTS0571027
Additional Subjects Toxicology ; Health effects ; Toxic substances ; B-aminocrotonitrile ; Acute toxicity ; Mammals ; Rats ; Oral ; Gavage ; Parenteral ; Intraperitoneal ; Mice ; Guinea pigs ; Dermal ; CAS No 1118-61-2
Holdings
Library Call Number Additional Info Location Last
Modified
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Status
NTIS  OTS0571027 Most EPA libraries have a fiche copy filed under the call number shown. Check with individual libraries about paper copy. 05/27/2010
Collation 5p
Abstract
The report pertains to 3-amino-2-butenenitrile (synonym: beta-aminoctotonitrile) (CAS No. 1118-61-2) and is being submitted because of lethality with central nervous system signs observed in an acute oral toxicity test in rats and mice. The oral LDa is 50 mg/kg in rats and 50-100 mg/kg in mice. The material is also a strong skin irritant and its dermal LDa is 0.5-1.0 g/kg in guinea pigs. The report is being identified as a study involving other than human effects (Unit II.B.2.b of CAP Agreement).