Record Display for the EPA National Library Catalog

RECORD NUMBER: 8 OF 10

Main Title Mucus Glycoprotein Secretion by Tracheal Explants: Effects of Pollutants.
Author Last, Jerold A. ; Kaizu, Tokio ;
CORP Author California Primate Research Center, Davis.;Health Effects Research Lab., Research Triangle Park, NC.
Year Published 1982
Report Number EPA-R-805355; EPA-600/J-82-208;
Stock Number PB82-250622
Additional Subjects Glycoproteins ; Trachea ; Air pollution ; Mucus ; Culture media ; Tissues(Biology) ; Rats ; In vivo analysis ; In vitro analysis ; Ozone ; Reprints ;
Holdings
Library Call Number Additional Info Location Last
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Status
NTIS  PB82-250622 Some EPA libraries have a fiche copy filed under the call number shown. 07/26/2022
Collation 9p
Abstract
Tracheal slices incubated with radioactive precursors in tissue culture medium. The authors have used anin vitro approach, a combined method utilizing exposure to pneumotoxins in vivo coupled with quantitation of mucus secretion rates in vitro, to study the effects of inhaled pollutants on mucus biosynthesis by rat airways. In addition, the authors have purified the mucus glycoproteins secreted by rat tracheal explants in order to determine putative structural changes that might be the basis for the observed augmented secretion rates after exposure of rats to H2SO4 aerosols in combination with high ambient levels of ozone.