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Main Title Identification of Two Glucuronide Metabolites of Doxylamine via Thermospray/Mass Spectrometry and Thermospray/Mass Spectrometry/Mass Spectrometry.
Author Korfmacher, W. A. ; Holder, C. L. ; Betowski, L. D. ; Mitchum, R. K. ;
CORP Author Environmental Monitoring Systems Lab., Las Vegas, NV. ;National Center for Toxicological Research, Jefferson, AR.
Year Published 1987
Report Number EPA/600/J-87/173;
Stock Number PB88-159751
Additional Subjects Mass spectroscopy ; Chromatographic analysis ; Ionization ; Metabolism ; Toxicology ; Reprints ; Doxylamine ; Glucuronates ; Bendectin
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NTIS  PB88-159751 Some EPA libraries have a fiche copy filed under the call number shown. 07/26/2022
Collation 5p
Abstract
Analysis of a high-pressure liquid chromatography fraction containing two urinary glucuronide metabolites of doxylamine by thermospray mass spectrometry (TSP/MS) provided (MH)+ ions for each metabolite. TSP/MS/MS of the (MH)+ ions provided a fragment ion characteristic of these metabolites. The results demonstrate the utility of TSP/MS analysis for biologically derived glucuronide metabolites. (Copyright (c) Journal of Analytical Toxicology, 1987.)