Record Display for the EPA National Library Catalog

RECORD NUMBER: 13 OF 252

Main Title Bacterial Reverse Mutation Assay using Vapor-Phase Exposure for 1,6-Hexamethylene Diisocyanate, with Cover Letter dated 09/20/1998.
CORP Author Microbiological Associates, Bethesda, MD.; Chemical Manufacturers Association, Washington, DC.; Environmental Protection Agency, Washington, DC. Office of Toxic Substances.
Year Published 1999
Stock Number OTS0573907
Additional Subjects Toxicology ; Health effects ; 1 ; 6-hexamethylene diisocyante ; Genotoxicity ; Gene mutations ; Bacteria ; In vitro ; CAS No 822-06-0
Holdings
Library Call Number Additional Info Location Last
Modified		 Checkout
Status
NTIS  OTS0573907 Some EPA libraries have a fiche copy filed under the call number shown. 07/26/2022
Collation 68p
Abstract
The test substance, 1,6 - hexamethylene diisocyanate, was tested in the bacterial reverse mutation assay using S. typhimwium tester strains TA98, TA100, TA1535 and TA1537 in the presence and absence of Aroclor-induced rat liver S9. The assay was performed in two phases, using the vapor-phase exposure method. The first phase, the preliminary toxicity assay, was used to establish the dose range for the mutagenicity assay. The second phase, the mutagenicity assay, was used to evaluate the mutagenic potential of the test substance.