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RECORD NUMBER: 6 OF 72

Main Title Applications of toxicogenomics in safety evaluation and risk assessment /
Other Authors
Author Title of a Work
Boverhof, Darrell R.
Gollapudi, B. Bhaskar.
Publisher John Wiley & Sons,
Year Published 2011
OCLC Number 671385938
ISBN 9780470449820 (cloth); 0470449829 (cloth); 9781118001042 (oBook); 1118001044 (oBook); 9781118008980 (ePub); 1118008987 (ePub); 9781118001035 (ePDF); 1118001036 (ePDF)
Subjects Genetic toxicology ; Toxicity testing ; Health risk assessment ; Toxicogenetics ; Risk Assessment
Holdings
Library Call Number Additional Info Location Last
Modified
Checkout
Status
EKCM  RA1224.3.A67 2011 CEMM/GEMMD Library/Gulf Breeze,FL 08/29/2011
ELBM  RA1224.3.A679 2011 AWBERC Library/Cincinnati,OH 12/31/2012
Collation xiii, 377 p. : ill. (some col.) ; 25 cm.
Notes
Includes bibliographical references and index.
Contents Notes
Toxicology, "omics" technologies, and toxicogenomics : a primer -- Introduction to human health risk assessment -- Practical considerations for the application of toxicogenomics to risk assessment -- early experience, current drivers, and a path forward -- Approaches and practical considerations for the analysis of toxicogenomics data -- Genomics in identifying mutagenic mode of action in carcinogenesis -- Application of genomics for predicting and understanding the mode of action for non-genotoxic carcinogens -- Genomics in characterizing endocrine toxicity -- Studying organ specific toxicity using gene expression profiling -- Toxicogenomic studies in human populations -- Toxicogenomics applied to ecological risk assessment -- Analysis of transcriptomic dose response data for toxicology and risk assessment -- Toxicogenomics as a tool for validating animal to human extrapolations in chemical risk assessment: concepts, applications and challenges -- Toxicogenomics and animal alternatives -- Toxicogenomics and the regulatory framework -- Standardization of gene expression information for the safety evaluation -- activities in Japan -- Applying transcriptional profiling in drug safety evaluation -- Reframing the risk assessment paradigm : towards a systems biology approach.