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RECORD NUMBER: 47 OF 49

Main Title Toxicological Significance of the Chemical Reactions of Aqueous Chlorine and Chloramines.
Author Scully, F. E. ; Mazina, K. ; Sonenshine, D. E. ; Ringhand, H. P. ;
CORP Author Old Dominion Univ., Norfolk, VA.;Health Effects Research Lab., Research Triangle Park, NC.
Year Published 1988
Report Number EPA-R-813092; EPA/600/D-88/012;
Stock Number PB88-160270
Additional Subjects Toxicology ; Chlorine ; Disinfectants ; Oxidizers ; Chemical reactions ; Gastrointestinal system ; Potable water ; Water treatment ; Public health ; Chloramines ; Biological effects ; Toxic substances
Holdings
Library Call Number Additional Info Location Last
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Status
NTIS  PB88-160270 Some EPA libraries have a fiche copy filed under the call number shown. 07/26/2022
Collation 14p
Abstract
When a strong oxidizing agent, like a drinking water disinfectant, is ingested, it dissolves in the highly organic solutions of the gastrointestinal tract, including saliva and stomach fluid, and comes in contact with tissues. Because it is a strong oxidant, it can be expected to react with organic biomolecules present. Since aqueous chlorine and, to an ever increasing extent, inorganic monochloramine, are widely used disinfectants, it is important to determine what reactions these oxidants can undergo in the body and whether their products exhibit adverse health effects or can be detoxified. The reactions of aqueous chlorine and monochloramine with biomolecules and in biological systems will be reviewed with the intent of assessing their toxicological significance.