Record Display for the EPA National Library Catalog


OLS Field Name OLS Field Data
Main Title Experimental Infection of Mongrel Dogs with 'Giardia lamblia' Cysts and Cultured Trophozoites.
Author Hewlett, Erik L. ; Andrews, Jr., John S. ; Ruffier, Juanita ; Schaefer, III, Frank W. ;
CORP Author Case Western Reserve Univ., Cleveland, OH.;Health Effects Research Lab., Cincinnati, OH.;Public Health Service, Rockville, MD.
Year Published 1981
Report Number PHS-AI-15351; EPA-600/J-82-088;
Stock Number PB83-145243
Additional Subjects Giardiasis ; Parasitic diseases ; Dogs ; Gastrointestinal diseases ; Infectious diseases ; Protozoal diseases ; Reprints ; Giardia lamblia
Library Call Number Additional Info Location Last
NTIS  PB83-145243 Most EPA libraries have a fiche copy filed under the call number shown. Check with individual libraries about paper copy. 06/23/1988
Collation 7p
In light of recent epidemiologic data implicating wild and domestic animals in the transmission of giardiasis, a study was undertaken to determine whether mongrel dogs could be infected with Giardia lamblia. After careful screening by stool examination (a minimum of six stools examined per week for three weeks), dogs were channenged orally with G. lamblia cysts from human stool or trophozoites from an axenic culture. Three of eight dogs became infected with cysts, and two of three became infected with trophozoites. Latency periods and the course of cyst excretion were similar to those observed in humans, but the dogs were not clinically ill. These data support the concept of interspecies transmission of Giardia and demonstrate that infection can be transmitted by the trophozoite form as well as by cysts.