Record Display for the EPA National Library Catalog


Main Title In situ Assessment of Genotoxic Hazards of Environmental Pollution.
Author Sandhu, S. S. ; Lower, W. R. ;
CORP Author Health Effects Research Lab., Research Triangle Park, NC. Genetic Toxicology Div. ;Missouri Univ.-Columbia. Environmental Trace Substances Research Center.
Publisher c1989
Year Published 1989
Report Number EPA/600/J-89/041;
Stock Number PB90-103607
Additional Subjects Indicator species ; Environmental surveys ; Animals ; Plants ; Exposure ; Fishes ; Liver neoplasms ; Mutations ; Reprints ; Toxic substances ; Mutagenicity tests ; Biological effects ; Sister chromatid exchange ; Micronucleus test ; Environmental pollution ; Gallbladder neoplasms
Library Call Number Additional Info Location Last
NTIS  PB90-103607 Some EPA libraries have a fiche copy filed under the call number shown. 07/26/2022
Collation 13p
The potential impact of environmental pollutants on human health can be evaluated by laboratory analysis of environmental samples or by measurement of biological effects on indigenous populations and/or specific test organisms placed in the environment to be monitored. The organisms most commonly used to assess mutagenicity under real world conditions are flowering plants, wild and captive mammals, and aquatic vertebrates. Plant species have been used to monitor ambient air quality around several major industrial cities in the USA, nuclear power plants, and industrial waste sites, and also to assess potential health effects of municipal sewage sludges. Domestic animals can be used as sentinels to provide information on effects of contaminants in the environment and have been used to a limited extent to evaluate environmental influences on the occurrence of breast cancer and osteosarcoma. Cytogenetic analysis from feral and wild animals has been employed to assess health hazards and prioritize clean-up efforts at hazardous waste sites. Aquatic animals have been used more often than terrestrial animals or plants to identify and characterize the genotoxic effects of environmental pollution.