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RECORD NUMBER: 91 OF 237

Main Title Hepatic Enzyme Systems as Biochemical Indicators of the Effects of Contaminants on Reproduction of Chinook Salmon 'Oncorhynchus tschawytscha'.
Author Ankley, G. T. ; Tillitt, D. E. ; Gooch, J. W. ; Giesy., J. P. ;
CORP Author Environmental Research Lab.-Duluth, MN. ;Michigan State Univ., East Lansing. Center for Environmental Toxicology. ;Woods Hole Oceanographic Institution, MA. Dept. of Biology.;Michigan Univ., Ann Arbor. Sea Grant Program.;Michigan Agricultural Experiment Station, East Lansing.
Publisher c1989
Year Published 1989
Report Number EPA/600/J-89/476;
Stock Number PB91-115923
Additional Subjects Enzymes ; Salmon ; Water pollution ; Lake Michigan ; Reproduction(Biology) ; Liver ; Chlorine organic compounds ; Biphenyl ; Concentration(Composition) ; Biochemistry ; Exposure ; Aromatic polycyclic hydrocarbons ; Furans ; Mortality ; Correlation ; Eggs ; Exposure ; Reprints ; Foreign technology ; Biochemical indicators ; Polychlorinated biphenyl ; Dibenzodioxin ; Oncorhynchus tschawytscha
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NTIS  PB91-115923 Some EPA libraries have a fiche copy filed under the call number shown. 07/26/2022
Collation 10p
Abstract
The reproductive success of 30 female Lake Michigan chinook salmon (Oncorhynchus tschawytscha) was evaluated and compared to the status of two hepatic enzyme systems proposed as sensitive biochemical indicators of exposure to planar polychlorinated aromatic hydrocarbons, including certain polychlorinated biphenyls, polychlorinated dibenzofurans and polychlorinated dibenzodioxins. Fertilizability, hatchability and egg and fry mortality varied significantly among the fish. Hepatic monooxygenase and glutathione S-transferase activities and cytochrome P-450E concentration also varied markedly among the fish. There was, however, little correlation between reproductive success and the three biochemical indicators of contaminant exposure.