Record Display for the EPA National Library Catalog


OLS Field Name OLS Field Data
Main Title Combined Use of Biochemical Indicators to Assess Sublethal Pollution Effects on the Gulf Killifish ('Fundulus grandis').
Author Schoor, W. P. ; Williams, D. E. ; Lech, J. J. ;
CORP Author Environmental Research Lab., Gulf Breeze, FL. ;Medical Coll. of Wisconsin, Inc., Milwaukee. Dept. of Pharmacology and Toxicology.
Year Published 1988
Report Number EPA/600/J-88/106;
Stock Number PB88-251699
Additional Subjects Fishes ; Water pollution ; Toxicology ; Chico Bayou ; Oxidoreductases ; Liver ; Reprints ; Fundulus grandis ; Gulf killifish ; Water pollution effects(Animals) ; Water pollution detection ; Enzyme induction ; Cytochrome P-450 ; Anyl hydrocarbon hydroxylases ; Ethoxyresorufin O-deethylase
Library Call Number Additional Info Location Last
NTIS  PB88-251699 Most EPA libraries have a fiche copy filed under the call number shown. Check with individual libraries about paper copy. 12/29/1988
Collation 7p
Sublethal biochemical markers were used to identify liver enzyme induction in fish from a bayou in Pensacola, Florida. Gulf killifish, Fundulus grandis, from a nonpolluted site were used in the study which included laboratory-induced fish and their various controls as well as the fish captured in the bayou. The biochemical markers tested were liver to body weight ratios, total content of cytochrome P-450, mixed function oxygenase and ethoxyresorufin-O-deethylase activities, and the specific induction of the ML4b isozyme of the cytochrome P-450 system. The findings suggest that enzyme induction occurred at a sublethal level, indicating the presence of liver enzyme inducing substances in the bayou.