Record Display for the EPA National Library Catalog


Main Title Summary Review of Health Effects Associated with Hydrogen Fluoride and Related Compounds. Health Issue Assessment.
Author Theissen, K. ;
CORP Author Environmental Protection Agency, Research Triangle Park, NC. Environmental Criteria and Assessment Office. ;Oak Ridge National Lab., TN.
Publisher Dec 88
Year Published 1988
Report Number EPA/600/8-89/002F ;ECAO-R-0131;
Stock Number PB89-220495
Additional Subjects Hydrogen fluoride ; Toxicity ; Exposure ; Industrial atmospheres ; Food ; Water ; Risk assessment ; Carcinogenesis ; Biological effects ; Dose-response relationships ; Air pollutants ; Reference dose
Internet Access
Description Access URL
Library Call Number Additional Info Location Last
NTIS  PB89-220495 Some EPA libraries have a fiche copy filed under the call number shown. 07/26/2022
Collation 65p
The average daily hydrogen fluoride intake is on the order of 1.2-3.0 mg/day from food and water, respectively. For children and adults who do not have any occupational exposure to or do not live in the immediate vicinity of industrial operations that emit HF. Use of fluoridated dentifrices contributes an additional 0.25 mg/day; less than 0.1 mg/day comes from inhaled fluoride. This total exposure level (approximately 0.06 mg/kg/day) has been shown to have a cariostatic effect, especially in children, and is generally considered to be the No Observed Adverse Effect Level (NOAEL). This level of exposure has been established as the oral reference dose (RfD) by the Agency, although it should be noted that very mild dental fluorosis (mottling) has been observed in about 20% of the people who are chronically exposed at this level. The possible carcinogenic potential or chronic exposure to fluoride has been investigated, and the Agency has stated that there is not enough information to conclude that fluoride presents a cancer risk to humans.