| Main Title |
Initial Submission: TSCA Health and Safety Study Cover Sheet with Continuation Sheet Summarizing Pilot Study on Developmental Toxicity in Rats after Oral Administration of ALM 2647, dated 10/05/99. |
| CORP Author |
Bayer A.G., Wuppertal (Germany, F.R.).;Environmental Protection Agency, Washington, DC. Office of Toxic Substances. |
| Publisher |
12 Oct 1999 |
| Year Published |
1999 |
| Report Number |
8EHQ-1099-14565; |
| Stock Number |
OTS-0559812 |
| Additional Subjects |
Fungicides ;
Toxicity ;
Rats ;
Laboratory animals ;
Oral ingestion ;
Gavage ;
Tolerance(Physiology) ;
Dosage ;
Fetuses ;
Pregnancy ;
Body weight ;
Females ;
ALM 2647
|
| Holdings |
| Library |
Call Number |
Additional Info |
Location |
Last
Modified |
Checkout
Status |
| NTIS |
OTS-0559812 |
Some EPA libraries have a fiche copy filed under the call number shown. |
|
07/26/2022 |
|
| Collation |
8p |
| Abstract |
Eight mated female Wistar rats each were daily treated orally by gavage with ALM 2647 in 0.5% aqueous carboxymethylcellulose from day 6 to day 19 p.c. with doses of 0, 10, 30 and 100 mg/kg body weight (bw)/day (dose-volume 10 ml/kg bw). The fetuses were delivered by cesarean section on day 20 p.c. Investigations were performed on general tolerance of the test compound by the females as well as on its effect on intrauterine development. 2/3 of fetuses underwent skeletal evaluation while 1/3 of fetuses were evaluated viscerally. |
