Record Display for the EPA National Library Catalog

RECORD NUMBER: 93 OF 93

Main Title

USEPA Status Report: Pyrazole with Cover Letter dated 08/25/89. (Sanitized).

CORP Author

Environmental Protection Agency, Washington, DC. Office of Toxic Substances.

Publisher

10 Jul 1989

Year Published

1989

Report Number

FYI-OTS-0389-0677S;

Stock Number

OTS-0000677-1

Additional Subjects

Pyrzole ; Toxicity ; Tests ; Fetus ; Rats ; Gestation ; Dosimitry ; Mice ; Teratology ; CAS No 288-13-1 ; Developmental toxicity ; Embryo toxicology ; Maternal toxicity

Holdings

Library	Call Number	Additional Info	Location	Last Modified	Checkout Status
NTIS	OTS-0000677-1	Some EPA libraries have a fiche copy filed under the call number shown.		07/26/2022

Collation

12p

Abstract

The information presented in the published studies cited in the FYI submission indicates that pyrazole can cause developmentally toxic effects following intraperitoneal injection in mice and oral administration to rats. Giknis and Damjanov (1982) found that intraperitoneal injections of pyrazole at a dose of 6 mg/kg/day to pregnant Swiss Webster mice on days 8, 10, 12 and 14 of gestation resulted in reduced litter size and reduced fetal weight.