Record Display for the EPA National Library Catalog

RECORD NUMBER: 44 OF 93

Main Title Exploration of perinatal pharmacokinetic issues /
Publisher National Center for Environmental Assessment,
Year Published 2001
Report Number EPA/600/P-01/004; 68-C-99-238
OCLC Number 320466374
Subjects Fetus--Effect of drugs on ; Perinatal pharmacology ; Drugs--Physiological effect
Internet Access
Description Access URL
http://cfpub.epa.gov/si/si_public_record_report.cfm?dirEntryId=29420
http://www.epa.gov/raf/publications/exploration-perinatal-pharmacokinetic.htm
Holdings
Library Call Number Additional Info Location Last
Modified
Checkout
Status
EJAD  EPA 600/P-01/004 Region 3 Library/Philadelphia, PA 05/11/2009
Edition Final
Collation 57 p. ; 28 cm.
Notes
"EPA/600/P-01/003." "May 10, 2001." "Contract no. 68-C-99-238, Task Order 13." Includes bibliographical references.
Contents Notes
This paper brings together a large amount of previously disparate information. The first two sections of the paper cover relative activities and maturation of many enzyme systems, and relative tissue distribution and excretion capacities. The final sections provide specific information on transplacental transfer, plasma to milk transfer, and consideration of the blood-brain barrier. An understanding of these components and their impact on childhood exposures will be important to future model development and considerations of appropriate risk assessment approaches.