The teratogenic potential of DOW CORNING Antifoam A Compound, Food Grade (hereafter referred to as DOW CORNING Antifoam A Compound) administered in the diet was studied in rabbits. Pregnant New Zealand white rabbits were given food grade DOW CORNING Antifoam A Compound in the diet at concen- trations of 0, 0.5, 1.0, and 2.5% from the morning of day 6 through the morning of day 19 of gestation. There were no overt signs of toxicity in the dams, and no statistically significant differences in feed consumption at any level compared to the control group. There was no evidence of adverse effects in mean maternal body weight or liver weight of the treated females. The incidence of resorptions among the total fetal population was not altered by feeding DOW CORNING Antifoam A Compound to pregnant rabbits at the three dictary levels. Term fetuses were examined by standard teratological techniques. Male and female pup weights were unaffected by the maternal treatment. DOW CORNING Antifoam A Compound had no statistically significant adverse effects on the incidence of external, visceral or skeletal abnormalities. On the basis of those results, it is concluded that DOW CORNING Antifoam A Compound is not embryotoxic or teratogenic in rabbits at dietary levels up to 2.5%.