||Inhalation Study of the Effects of Octamethylcyclotetrasiloxane (D4) Exposure on the preovulatory LH Surge in Ovariectomized Femal Rats.
Stump, D. G. ;
||WIL Research Laboratories, Inc., Ashland, OH. ;Dow Corning Corp., Midlands, MI. Health and Environmental Sciences Dept.;Environmental Protection Agency, Washington, DC. Office of Toxic Substances.
||7 Sep 2001
Inhalation exposure ;
Health effects ;
Female rats ;
Sprague-Dawley rats ;
||Some EPA libraries have a fiche copy filed under the call number shown.
This study was conducted to evaluate the potential of octamethylcyclotetrasiloxane (D4) to affect the preovulatory luteinizing hormone (LH) surge in overiectomized female rats. In order to synchronize the estrous cycles of the females, the animals were ovariectomized and treated with estradiol via a subcutaneous implant.