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Main Title Human drug metabolism : from molecular biology to man /
Other Authors
Author Title of a Work
Jeffery, Elizabeth H.
Publisher CRC Press,
Year Published 1993
OCLC Number 26098903
ISBN 0849378109 (acid-free paper)
Subjects Drugs--Metabolism ; Drugs--Metabolic detoxification ; Biotransformation ; Pharmaceutical Preparations--metabolism ; Sistema digestivo (farmacologia)--larpcal ; Farmacologia geral e farmacocinetica--larpcal
Library Call Number Additional Info Location Last
EJEM  RM301.55.H86 1992 OCSPP Chemical Library/Washington,DC 01/31/2003
Collation 158 p. : ill. ; 27 cm.
Includes bibliographical references and index.
Contents Notes
Introduction / E.H. Jeffery -- Human cytochrome P450 enzymes and chemical carcinogenesis / F.P. Guengerich and T. Shimada -- cDNA-directed expression of human cytochrome P450 / F.J. Gonzalez and H.V. Gelboin -- Human P450 enzymes associated with the mephenytoin 4-hydroxylation polymorphism / J.L. Raucy and J.M. Lasker -- Assessment of drug oxidation in man in vivo / D.D. Breimer -- Covalent binding of acetaminophen estimated from protein adducts / H.E. Poulsen, D.W. Roberts and J.A. Hinson -- Xenobiotic metabolism studies with human liver / D.E. Chapman ... {et al.} -- Epoxide hydrolases: immunochemical detection in human tissues / T.M. Guenthner ... {et al.} -- Conjugation reactions in man: studies with diflunisal / R.K. Verbeeck -- Analysis of the specificity of human liver glucuronidation using cloned and stably expressed UDP-glucuronosyltransferases / B. Burchell ... {et al.} -- Properties of human cytosolic sulfotransferases involved in drug metabolism / C.N. Falany and J.A. Roth -- Acetylation pharmacogenetics / U.A. Meyer ... {et al.}. (cont) Glutathione S-transferase localization in human tumors / D.J. Harrison -- Glutathione conjugation in man / T.M.T. Mulders, D.D. Breimer and G.J. Mulder -- Alteration of drug biotransformation during the operation of host defense mechanism in humans / K.W. Renton.