| Main Title |
Determination of Pentachlorophenol in Urine: The Importance of Hydrolysis. |
| Author |
Edgerton, Thomas R. ;
Moseman, R. F. ;
|
| CORP Author |
Heath Effects Research Lab., Research Triangle Park, NC. Environmental Toxicology Div. |
| Year Published |
1978 |
| Report Number |
EPA/600/J-79/009; |
| Stock Number |
PB-294 920 |
| Additional Subjects |
Urine ;
Chemical analysis ;
Pesticides ;
Hydrolysis ;
Extraction ;
Biological extracts ;
Chlorine organic compounds ;
Phenol/pentachloro ;
Electron capture gas chromatography ;
Reprints
|
| Holdings |
| Library |
Call Number |
Additional Info |
Location |
Last
Modified |
Checkout
Status |
| NTIS |
PB-294 920 |
Some EPA libraries have a fiche copy filed under the call number shown. |
|
07/26/2022 |
|
| Collation |
5p |
| Abstract |
A gas chromatographic method for more reliable determination of pentachlorophenol (PCP) in urine has been developed. After hydrolysis and extraction the sample was reacted with diazomethane to produce the methyl ether of PCP prior to analysis by electron-capture gas chromatography. An acid alumina column clean-up system was developed to remove interferences from the sample extracts and allow detectability of 1 ppb PCP. Average recoveries of greater than 90% were obtained from urine fortified with known amounts of PCP. The importance of hydrolysis and comparisons of present methodologies will also be presented. |
