Abstract |
The Office of Pesticide Programs (OPP) models daily aquatic pesticide exposure values for 30 years in its risk assessments. However, only a fraction of that information is typically used in these assessments. The population model employed herein is a deterministic, density-dependent periodic matrix model for integrating time-varying pesticide exposure effects on the marine invertebrate Americamysis bahia. The external exposure concentrations are converted to time-varying scaled internal concentrations by coupling a one-compartment toxicokineticstoxicodynamics model with the matrix model. Several exposure scenarios (each with the same risk as determined by OPP’s traditional approach) were created within which population modeling documented different risk conclusions than assessments based on the traditional approach. Population modeling incorporates all available toxicological and exposure data, making a more complete assessment of the potential risk of time-varying aquatic concentrations. |