| Main Title |
Actions of pesticides and other drugs on the male reproductive system. |
| Author |
Thomas, John Arlen.
|
| CORP Author |
West Virginia Univ. Medical Center, Morgantown. Dept. of Pharmacology.;National Environmental Research Center, Research Triangle Park, N.C. Pesticides and Toxic Substances Effects Lab. |
| Publisher |
US Environmental Protection Agency, Pesticides and Toxic Substances Effects Laboratory, |
| Year Published |
1974 |
| Report Number |
EPA/650-1-74-011; EPA-R-801650; PB237381 |
| Stock Number |
PB-237 381 |
| OCLC Number |
37391415 |
| Subjects |
Reproductive toxicology
|
| Additional Subjects |
Pesticides ;
Reproductive system ;
Sex hormones ;
Insecticides ;
Males ;
Drugs ;
Mice ;
Laboratory animals ;
Experimental data ;
Toxicology ;
Physiological effects ;
Prostrate gland ;
Liver ;
DDT ;
Dieldrin ;
Chlorine organic compounds ;
Metabolism ;
Herbicides ;
Androgens ;
Tritium ;
Carbamates ;
Labeled substances ;
Parathion ;
T 2-4-5 ;
Acetic acid/trichlorophenoxy ;
Carbaryl
|
| Internet Access |
|
| Holdings |
| Library |
Call Number |
Additional Info |
Location |
Last
Modified |
Checkout
Status |
| EJBD ARCHIVE |
EPA 650-1-74-011 |
|
Headquarters Library/Washington,DC |
05/27/2014 |
| EJED |
EPA 650-1-74/011 |
|
OCSPP Chemical Library/Washington,DC |
07/01/2005 |
| ERAD |
EPA 650/1-74/011 |
|
Region 9 Library/San Francisco,CA |
03/18/2013 |
| NTIS |
PB-237 381 |
Some EPA libraries have a fiche copy filed under the call number shown. |
|
07/26/2022 |
|
| Collation |
viii, 34 pages : tables ; 27 cm. |
| Abstract |
DDT or dieldrin or 2,4,5 T administered to male mice caused significant reductions in the assimilation of androgens by sex accessory organs. DDT or dieldrin altered the metabolism of testosterone in the prostrate gland and in the liver. DDT-3H administration led to the detection of significant amounts of tritium in male reproductive organs. Unlike the organochlorine-type pesticides, neither carbaryl nor parathion administration altered androgen metabolism. The administration of carbaryl-14C led to detectable amounts of radioactivity in several organs of reproduction including the seminal vesicles, prostate gland and testes. The fungicide thiophanate and thiophante-methyl had no affect upon spermatogenesis or upon the metabolism of androgens. |
| Notes |
"EPA/650-1-74-011." "December 1974." "Grant No. R801650, ROAP No. 21AYL, Program Element No. 1EA078." Includes bibliographical references (pages 29-30). List of publications: pages 31-32. |
