Record Display for the EPA National Library Catalog


Main Title Actions of pesticides and other drugs on the male reproductive system.
Author Thomas, John Arlen.
CORP Author West Virginia Univ. Medical Center, Morgantown. Dept. of Pharmacology.;National Environmental Research Center, Research Triangle Park, N.C. Pesticides and Toxic Substances Effects Lab.
Publisher US Environmental Protection Agency, Pesticides and Toxic Substances Effects Laboratory,
Year Published 1974
Report Number EPA/650-1-74-011; EPA-R-801650; PB237381
Stock Number PB-237 381
OCLC Number 37391415
Subjects Reproductive toxicology
Additional Subjects Pesticides ; Reproductive system ; Sex hormones ; Insecticides ; Males ; Drugs ; Mice ; Laboratory animals ; Experimental data ; Toxicology ; Physiological effects ; Prostrate gland ; Liver ; DDT ; Dieldrin ; Chlorine organic compounds ; Metabolism ; Herbicides ; Androgens ; Tritium ; Carbamates ; Labeled substances ; Parathion ; T 2-4-5 ; Acetic acid/trichlorophenoxy ; Carbaryl
Internet Access
Description Access URL
Library Call Number Additional Info Location Last
EJBD ARCHIVE EPA 650-1-74-011 Headquarters Library/Washington,DC 05/27/2014
EJED  EPA 650-1-74/011 OCSPP Chemical Library/Washington,DC 07/01/2005
ERAD  EPA 650/1-74/011 Region 9 Library/San Francisco,CA 03/18/2013
NTIS  PB-237 381 Some EPA libraries have a fiche copy filed under the call number shown. 07/26/2022
Collation viii, 34 pages : tables ; 27 cm.
DDT or dieldrin or 2,4,5 T administered to male mice caused significant reductions in the assimilation of androgens by sex accessory organs. DDT or dieldrin altered the metabolism of testosterone in the prostrate gland and in the liver. DDT-3H administration led to the detection of significant amounts of tritium in male reproductive organs. Unlike the organochlorine-type pesticides, neither carbaryl nor parathion administration altered androgen metabolism. The administration of carbaryl-14C led to detectable amounts of radioactivity in several organs of reproduction including the seminal vesicles, prostate gland and testes. The fungicide thiophanate and thiophante-methyl had no affect upon spermatogenesis or upon the metabolism of androgens.
"EPA/650-1-74-011." "December 1974." "Grant No. R801650, ROAP No. 21AYL, Program Element No. 1EA078." Includes bibliographical references (pages 29-30). List of publications: pages 31-32.