Record Display for the EPA National Library Catalog

RECORD NUMBER: 651 OF 780

Main Title Short-Term Carcinogenesis and Mutagenesis Bioassays of Unregulated Automotive Emissions.
Author Huisingh, J. L. ;
CORP Author Health Effects Research Lab., Research Triangle Park, NC.
Year Published 1981
Report Number EPA-600/J-82-056;
Stock Number PB84-101815
Additional Subjects Bioassay ; Exhaust gases ; Toxicology ; Risk ; Reprints ; Carcinogenesis ; Mutagenesis ; Automobile exhaust ; Health risks ; Environmental health
Holdings
Library Call Number Additional Info Location Last
Modified
Checkout
Status
NTIS  PB84-101815 Some EPA libraries have a fiche copy filed under the call number shown. 07/26/2022
Collation 14p
Abstract
Evaluation of the potential risk of a chemical or environmental emission causing chronic health effects requires data from one or more of the following sources: epidemiologic and clinical studies of human exposure and effects; chronic (long term) bioassays in animals; and short-term bioassays in animals, animal and human cells, insects, plants, and microorganisms. Although it is advantageous to have data from as many different sources and bioassays systems as possible, human and chronic animal data are essential to the definitive determination of whether a substance poses a carcinogenic hazard to humans. Often, however, such data are not available for the evaluation of emissions from new or alternative technologies. In particular, data from long-term human or animal studies are rarely available before the introduction of new emission sources. Short-term tests, therefore, provide important suggestive evidence of a substance's potential to cause genotoxic effects.