Record Display for the EPA National Library Catalog

RECORD NUMBER: 2 OF 3

OLS Field Name OLS Field Data
Main Title Synchronization of Rapid Globin Expression in Murine Erythroleukemic Cells.
Author Zucker, R. M. ;
CORP Author Papanicolaou Cancer Research Inst., Miami, FL.;Health Effects Research Lab., Research Triangle Park, NC.
Year Published 1985
Report Number EPA/600/J-85/412;
Stock Number PB86-213725
Additional Subjects Blood ; Hemoglobin ; Reprints ; Butyric acid ; Murine erythroleukemia cells ; DMSO
Holdings
Library Call Number Additional Info Location Last
Modified
Checkout
Status
NTIS  PB86-213725 Most EPA libraries have a fiche copy filed under the call number shown. Check with individual libraries about paper copy. 06/21/1988
Collation 7p
Abstract
The addition of butyric acid (BA) to murine erythroleukemia cells (MELC) produces the expression of primarily A and E2 hemoglobins while DMSO incubation produces the expression of primarily A hemoglobin. Preincubation of MELC with DMSO followed by BA induction accelerates the expression of hemoglobins in a synchronous manner, yielding the preferential synthesis of alpha and y globins, and E2 hemoglobin.