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RECORD NUMBER: 24 OF 58

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Main Title

Effects of Selected Water Toxicants on the in vitro Activity of Fish Carbonic Anhydrase.

Author

Christensen, G. M. ; Tucker., J. H. ;

CORP Author

Environmental Research Lab.-Duluth, Minn.

Year Published

1975

Report Number

EPA/600/J-76/010;

Stock Number

PB-265 284

Additional Subjects

Toxicity ; Catfishes ; Fishes ; Carbonic anhydrase inhibitors ; Metals ; Toxicology ; Physiochemical properties ; Water quality ; Dosage ; Water pollution ; In vitro analysis ; Enzyme inhibitors ; Pesticides ; Cations ; Anions ; Experimental data ; Blood ; Erythrocytes ; Physiochemical properties ; Reprints ; Ictalurus punctatus ; Water pollution effects(Animals) ; Chemicals ; Toxic substances

Holdings

Library	Call Number	Additional Info	Location	Last Modified	Checkout Status
NTIS	PB-265 284	Some EPA libraries have a fiche copy filed under the call number shown.		07/26/2022

Collation

14p

Abstract

Carbonic anhydrase (CA, carbonate hydro-lyase EC 4.2.1.1) from lysed red blood cells of the channel catfish (Ictalurus punctatus) was studied to determine physico-chemical kinetic properties and relative sensitivity to 56 chemicals of significance in water quality research. In general, enzyme activity was strongly reduced by heavy metal inorganic cations; less strongly by organometallic cations, some anions, and certain pesticides; and weakly inhibited by light metal cations and organometallic and organic compounds. Dose-response curves were qualitatively similar in most cases.

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