Record Display for the EPA National Library Catalog


Main Title Methods for Analyzing Occupational Cohort Data with Application to Lung Cancer in U.S. Uranium Miners: Techniques for Fitting and Checking Exposure-Time-Response Models.
Author Halpern, J. ; Whittemore., A. S. ;
CORP Author Stanford Univ., CA. School of Medicine.;National Science Foundation, Washington, DC.;Alfred P. Sloan Foundation, New York.
Publisher c1987
Year Published 1987
Report Number NIH-ES-00070 ;CA-23214; EPA/600/J-87/522;
Stock Number PB90-232349
Additional Subjects Epidemiology ; United States ; Tobacco ; Radon compounds ; Tables(Data) ; Reprints ; Occupational safety and health ; Cohort studies ; Uranium mines ; Radiation-induced neoplasms ; Lung neoplasms ; Radiation dose-response relationship ; Cocarcinogenesis
Library Call Number Additional Info Location Last
NTIS  PB90-232349 Some EPA libraries have a fiche copy filed under the call number shown. 07/26/2022
Collation 12p
Two methods were used to examine how lung cancer death rates vary with cumulative exposures to radiation and tobacco among uranium miners. The two methods produced similar results when death rate ratios were taken to be the product of radiation and tobacco effects. The estimates were discrepant when death rate ratios were taken to be the sum of radiation and tobacco effects. Both methods indicated better fit for the multiplicative model. It may be that cumulative exposures are inappropriate measures of the effects of radiation and tobacco on lung cancer death rates, as well as for other pollutants where the assumption of cumulative dose is the basis for risk assessments. (Copyright (c) 1987 Pergamon Journals Ltd.)