Record Display for the EPA National Library Catalog
RECORD NUMBER: 34 OF 44| Main Title | Maternal Transfer of Bioactive Polychlorinated Aromatic Hydrocarbons in Spawning Chinook Salmon ('Obchrhynchus tschawytscha'). | |||||||||||
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| Author | Ankley, G. T. ; Tillitt, D. E. ; Giesy., J. P. ; | |||||||||||
| CORP Author | Environmental Research Lab.-Duluth, MN.;Michigan State Univ., East Lansing. Center for Environmental Toxicology. | |||||||||||
| Publisher | c1989 | |||||||||||
| Year Published | 1989 | |||||||||||
| Report Number | EPA/600/J-89/483; | |||||||||||
| Stock Number | PB91-117556 | |||||||||||
| Additional Subjects | Aromatic polycyclic hydrocarbons ; Salmon ; Chlorinated hydrocarbons ; Reproduction(Biology) ; Reprints ; Maternal-fetal exchange ; Oncorhynchus tschawytscha ; Metabolic activation ; Dose-response relationships ; Enzyme induction ; Cultured tumor cells | |||||||||||
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| Collation | 5p | |||||||||||
| Abstract | The biological potency (relative to 2,3,7,8,-tetrachlorodibenzo-p-dioxin, TCDD) of planar polychlorinated aromatic hydrocarbons (PCHs) in extracts of eggs and flesh from spawning female chinook salmon (Oncorhynchus tschawytscha) from Lake Michigan was determined by measuring the induction of 7-ethoxyresorufin O-deethylase activity in H-4-II-E rat hepatoma cells. TCDD-equivalents in flesh and egg samples ranged from 0 to 115.8pg/g, and were approximately 5-fold greater in eggs than in flesh. These results suggest that the maternal transfer of PCHs may play a role in determining the reproductive success of Lake Michigan chinook salmon. (Copyright (c) 1990 Elsevier Science Publishers, Ltd., England.) |