In partnership with the Office of Solid Waste and Emergency Response and the regional offices, ORD sponsored three seminars in three different locations presenting information and guidance on the adverse impacts to human health resulting from the migration of vapors into residences and facilities from VOC contaminated groundwater and soils. Information was provided to aid decisionmakers in evaluating, assessing and characterizing vapor pathways resulting from this contamination. Following the issuance of the EPA draft vapor intrusion guidance document in November, 2002, these three seminars were conducted in San Francisco, CA in December of 2002; the second in Dallas, TX in January, 2003; and the third in Atlanta, GA, February, 2003. Over 750 people attended these meetings in total. Some of the topics covered during the seminars are presented in this CD-ROM including: theory, background, modeling, EPA guidance, site-specific pathway assessment, risk reduction measures, and risk communication considerations. This CD-ROM also provides an actual hands-on exercise which shows the user how to interpret and utilize the EPA guidance.