| Main Title |
Mutagenic potential of municipal sewage sludge and sludge amended soil / |
| Author |
Donnelly, K. C. ;
Brown, K. W. ;
Chisum, C. P.
|
| Other Authors |
|
| CORP Author |
Texas A and M Univ., College Station.;Health Effects Research Lab., Research Triangle Park, NC. |
| Publisher |
U.S. Environmental Protection Agency, Health Effects Research Laboratory, |
| Year Published |
1987 |
| Report Number |
EPA/600/D-87/259; EPA-R-812037 |
| Stock Number |
PB88-103841 |
| Subjects |
Sewage sludge--Environmental aspects--United States ;
Mutagenesis ;
Soils--Agricultural chemical content--United States ;
Soils--United States--Agricultural chemical content
|
| Additional Subjects |
Sludge ;
Mutagens ;
Waste water ;
Water treatment ;
Microbiology ;
Soil science ;
Sewage disposal ;
Environment effects
|
| Holdings |
| Library |
Call Number |
Additional Info |
Location |
Last
Modified |
Checkout
Status |
| NTIS |
PB88-103841 |
Some EPA libraries have a fiche copy filed under the call number shown. |
|
07/26/2022 |
|
| Collation |
32 pages ; 28 cm |
| Abstract |
Twelve municipal wastewater treatment plant sludges were collected and extracted by sequential extraction with methylene chloride and methanol on a Soxhlet apparatus. Each of three sludge fractions, i.e., methylene chloride, methanol, and a combined fraction (36 fractions total) were tested in the Salmonella/microsome assay. Only one of the sludge fractions induced a positive response in the absence of metabolic activation, and 12 fractions induced a doubling of revertant colonies at two or more consecutive dose levels with activation. The maximum mutagenic response observed with strain TA98 in a methylene chloride fraction was 120 net revertants at a dose level of 10 mg of extract per plate. The maximum response induced by the methanol and combined fractions was 89 net revertants, induced by a municipal sludge with 20% industrial contribution, and 61 net revertants, induced by a municipal sludge with 19% industrial contribution, respectively, both tested with strain TA98 at a dose level of 5 mg of extract per plate. These results indicate that there will be substantial differences in the mutagenic potential of municipal sludges from a single source and from different sources. |
| Notes |
Caption title. "Sept. 1987." Includes bibliographical references. "EPA/600/D-87/259." Microfiche. |
