The need for coordination on a multi-university basis was analyzed in terms of basic scientific and societal trends. Research coordination was defined as a two-directional and two-dimensional process (1) among members of the scientific community and (2) between the scientific community and the public - primarily government. The basic purpose is to overcome obstacles to the transfer of knowledge. The principal objective of regional coordination is the development of multi-disciplinary and multi-university research programs which address major public problems in a comprehensive and efficient manner and produce applicable results. Three interdependent functional areas for coordination were identified and discussed - information transfer, liaison and research planning. Institutional and administrative problems and alternatives were evaluated. (Author Modified Abstract)